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The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture

The nucleosome remodeling and deacetylase (NuRD) complex is essential for metazoan development but has been refractory to biochemical analysis. We present an integrated analysis of the native mammalian NuRD complex, combining quantitative mass spectrometry, cross-linking, protein biochemistry, and e...

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Detalles Bibliográficos
Autores principales: Low, Jason K.K., Silva, Ana P.G., Tabar, Mehdi Sharifi, Torrado, Mario, Webb, Sarah R., Parker, Benjamin L., Sana, Maryam, Smits, Callum, Schmidberger, Jason W., Brillault, Lou, Jackman, Matthew J., Williams, David C., Blobel, Gerd A., Hake, Sandra B., Shepherd, Nicholas E., Landsberg, Michael J., Mackay, Joel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908386/
https://www.ncbi.nlm.nih.gov/pubmed/33264611
http://dx.doi.org/10.1016/j.celrep.2020.108450