Anagliptin promotes apoptosis in mouse colon carcinoma cells via MCT-4/lactate-mediated intracellular acidosis

Cancer cells frequently exhibit an acidic extracellular microenvironment, where inversion of the transmembrane pH gradient is associated with tumor proliferation and metastasis. To elucidate a new therapeutic target against cancer, the current study aimed to determine the mechanism by which the dipe...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Qi, Qin, Xiaoling, Kou, Xiaotong, Li, Jingyu, Li, Zhongsha, Chen, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908463/
https://www.ncbi.nlm.nih.gov/pubmed/35317435
http://dx.doi.org/10.3892/etm.2022.11211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908463/
https://www.ncbi.nlm.nih.gov/pubmed/35317435
http://dx.doi.org/10.3892/etm.2022.11211

Ejemplares similares