Gelsolin impairs barrier function in pancreatic ductal epithelial cells by actin filament depolymerization in hypertriglyceridemia-induced pancreatitis in vitro

Gelsolin (GSN) is a calcium-regulated actin-binding protein that can sever actin filaments. Notably, actin dynamics affect the structure and function of epithelial barriers. The present study investigated the role of GSN in the barrier function of pancreatic ductal epithelial cells (PDECs) in hypert...

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Detalles Bibliográficos
Autores principales: Yang, Hui-Ying, Liang, Zhi-Hai, Xie, Jin-Lian, Wu, Qing, Qin, Ying-Ying, Zhang, Shi-Yu, Tang, Guo-Du
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908475/
https://www.ncbi.nlm.nih.gov/pubmed/35317441
http://dx.doi.org/10.3892/etm.2022.11219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908475/
https://www.ncbi.nlm.nih.gov/pubmed/35317441
http://dx.doi.org/10.3892/etm.2022.11219

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