Structure–Stability Relationship of NLRP3 Inflammasome-Inhibiting Sulfonylureas

[Image: see text] In recent drug development efforts, particular emphasis has been devoted to the chemical interference with the NLRP3 inflammasome. A series of 12 tailored sulfonylureas was designed, prepared through convergent syntheses with a final sodium hydride-promoted reaction of isocyanates...

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Detalles Bibliográficos
Autores principales: Keuler, Tim, Ferber, Dominic, Marleaux, Michael, Geyer, Matthias, Gütschow, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908490/
https://www.ncbi.nlm.nih.gov/pubmed/35284735
http://dx.doi.org/10.1021/acsomega.2c00125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908490/
https://www.ncbi.nlm.nih.gov/pubmed/35284735
http://dx.doi.org/10.1021/acsomega.2c00125

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