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Structure–Stability Relationship of NLRP3 Inflammasome-Inhibiting Sulfonylureas
[Image: see text] In recent drug development efforts, particular emphasis has been devoted to the chemical interference with the NLRP3 inflammasome. A series of 12 tailored sulfonylureas was designed, prepared through convergent syntheses with a final sodium hydride-promoted reaction of isocyanates...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908490/ https://www.ncbi.nlm.nih.gov/pubmed/35284735 http://dx.doi.org/10.1021/acsomega.2c00125 |