Computational Investigation of Structural Basis for Enhanced Binding of Isoflavone Analogues with Mitochondrial Aldehyde Dehydrogenase

[Image: see text] Isoflavone compounds are potent inhibitors against mitochondrial aldehyde dehydrogenase (ALDH2) for the treatment of alcoholism and drug addiction, and an in-depth understanding of the underlying structural basis helps design new inhibitors for enhanced binding. Here, we investigat...

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Detalles Bibliográficos
Autores principales: Zhang, Yongguang, Qiu, Yejie, Zhang, Haiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908493/
https://www.ncbi.nlm.nih.gov/pubmed/35284766
http://dx.doi.org/10.1021/acsomega.2c00032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908493/
https://www.ncbi.nlm.nih.gov/pubmed/35284766
http://dx.doi.org/10.1021/acsomega.2c00032

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