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Doxorubicin–NO Releaser Molecular Hybrid Activatable by Green Light to Overcome Resistance in Breast Cancer Cells

[Image: see text] The biological activity of a molecular hybrid (DXNO-GR) joining doxorubicin (DOX) and an N-nitroso moiety releasing nitric oxide (NO) under irradiation with the biocompatible green light has been investigated against DOX-sensitive (MCF7) and -resistant (MDA-MB-231) breast cancer ce...

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Detalles Bibliográficos
Autores principales: Parisi, Cristina, Moret, Francesca, Fraix, Aurore, Menilli, Luca, Failla, Mariacristina, Sodano, Federica, Conte, Claudia, Quaglia, Fabiana, Reddi, Elena, Sortino, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908524/
https://www.ncbi.nlm.nih.gov/pubmed/35284722
http://dx.doi.org/10.1021/acsomega.1c03988