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Structural basis of nanobodies neutralizing SARS-CoV-2 variants

Because of the evolutionary variants of SARS-CoV-2, development of broad-spectrum neutralizing antibodies resilient to virus escape is urgently needed. We identified a group of high-affinity nanobodies from camels immunized with receptor-binding domain (RBD) of SARS-CoV-2 spike protein and resolved...

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Detalles Bibliográficos
Autores principales: Shi, Zhenzhong, Li, Xiyang, Wang, Lu, Sun, Zengchao, Zhang, Haiwei, Chen, Xiaochen, Cui, Qianqian, Qiao, Huarui, Lan, Zhongyun, Zhang, Xin, Li, Xianheng, Li, Lingyun, Xu, Jianfeng, Gong, Rui, Fan, Chengpeng, Geng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908544/
https://www.ncbi.nlm.nih.gov/pubmed/35276082
http://dx.doi.org/10.1016/j.str.2022.02.011