Selective pressure of endocrine therapy activates the integrated stress response through NFκB signaling in a subpopulation of ER positive breast cancer cells

BACKGROUND: While estrogen receptor (ER) positive breast tumors generally respond well to endocrine therapy (ET), up to 40% of patients will experience relapse, either while on endocrine therapy or after ET is completed. We previously demonstrated that the selective pressure of tamoxifen activates t...

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Detalles Bibliográficos
Autores principales: Semina, Svetlana E., Pal, Purab, Kansara, Nidhi S., Huggins, Rosemary J., Alarid, Elaine T., Greene, Geoffrey L., Frasor, Jonna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908626/
https://www.ncbi.nlm.nih.gov/pubmed/35264224
http://dx.doi.org/10.1186/s13058-022-01515-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908626/
https://www.ncbi.nlm.nih.gov/pubmed/35264224
http://dx.doi.org/10.1186/s13058-022-01515-1

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