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Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer’s disease

Alzheimer’s disease (AD) is a major adult-onset neurodegenerative condition with no available treatment. Compelling reports point amyloid-β (Aβ) as the main etiologic agent that triggers AD. Although there is extensive evidence of detrimental crosstalk between Aβ and microglia that contributes to ne...

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Detalles Bibliográficos
Autores principales: Salvadores, Natalia, Moreno-Gonzalez, Ines, Gamez, Nazaret, Quiroz, Gabriel, Vegas-Gomez, Laura, Escandón, Marcela, Jimenez, Sebastian, Vitorica, Javier, Gutierrez, Antonia, Soto, Claudio, Court, Felipe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908658/
https://www.ncbi.nlm.nih.gov/pubmed/35264247
http://dx.doi.org/10.1186/s40478-022-01332-9