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RUNX3-mediated circDYRK1A inhibits glutamine metabolism in gastric cancer by up-regulating microRNA-889-3p-dependent FBXO4

BACKGROUND: Targeting glutamine metabolism is previously indicated as a potential and attractive strategy for gastric cancer (GC) therapy. However, the underlying mechanisms responsible for the modification of glutamine metabolism in GC cells have not been fully elucidated. Accordingly, the current...

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Detalles Bibliográficos
Autores principales: Liu, Haofeng, Xue, Qiu, Cai, Hongzhou, Jiang, Xiaohui, Cao, Guangxin, Chen, Tie, Chen, Yuan, Wang, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908664/
https://www.ncbi.nlm.nih.gov/pubmed/35272674
http://dx.doi.org/10.1186/s12967-022-03286-x