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EZH2 mitigates the cardioprotective effects of mesenchymal stem cell-secreted exosomes against infarction via HMGA2-mediated PI3K/AKT signaling

BACKGROUND: Mesenchymal stem cell-derived exosomes (MSC-EXO) have emerged as novel therapeutic strategies for myocardial infarction (MI). However, many questions remain untouched and unanswered regarding their roles in myocardial fibrosis. This study aimed to probe the therapeutic effects of MSC-EXO...

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Detalles Bibliográficos
Autores principales: Jiao, Wei, Hao, Jie, Xie, Yanan, Meng, Mingjie, Gao, Weinian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908676/
https://www.ncbi.nlm.nih.gov/pubmed/35264108
http://dx.doi.org/10.1186/s12872-022-02533-9