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SEEMLIS: a flexible semi-automated method for enrichment of methylated DNA from low-input samples

BACKGROUND: DNA methylation alterations have emerged as hallmarks of cancer and have been proposed as screening, prognostic, and predictive biomarkers. Traditional approaches for methylation analysis have relied on bisulfite conversion of DNA, which can damage DNA and is not suitable for targeted ge...

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Detalles Bibliográficos
Autores principales: Rodems, Tamara S., Juang, Duane S., Stahlfeld, Charlotte N., Gilsdorf, Cole S., Krueger, Tim E. G., Heninger, Erika, Zhao, Shuang G., Sperger, Jamie M., Beebe, David J., Haffner, Michael C., Lang, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908705/
https://www.ncbi.nlm.nih.gov/pubmed/35272673
http://dx.doi.org/10.1186/s13148-022-01252-4