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SEEMLIS: a flexible semi-automated method for enrichment of methylated DNA from low-input samples
BACKGROUND: DNA methylation alterations have emerged as hallmarks of cancer and have been proposed as screening, prognostic, and predictive biomarkers. Traditional approaches for methylation analysis have relied on bisulfite conversion of DNA, which can damage DNA and is not suitable for targeted ge...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908705/ https://www.ncbi.nlm.nih.gov/pubmed/35272673 http://dx.doi.org/10.1186/s13148-022-01252-4 |