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Probing Interplays between Human XBP1u Translational Arrest Peptide and 80S Ribosome

[Image: see text] The ribosome stalling mechanism is a crucial biological process, yet its atomistic underpinning is still elusive. In this framework, the human XBP1u translational arrest peptide (AP) plays a central role in regulating the unfolded protein response (UPR) in eukaryotic cells. Here, w...

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Detalles Bibliográficos
Autores principales: Di Palma, Francesco, Decherchi, Sergio, Pardo-Avila, Fátima, Succi, Sauro, Levitt, Michael, von Heijne, Gunnar, Cavalli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908735/
https://www.ncbi.nlm.nih.gov/pubmed/34881571
http://dx.doi.org/10.1021/acs.jctc.1c00796