Different tumorigenicity and distinct metastasis and gene signature between orthotopic and subcutaneous neuroblastoma xenografted mice

Patient-derived (PDX) and cell-derived (CDX) xenograft models are widely used in preclinical studies of human neuroblastoma. In this study, we constructed orthotopic and subcutaneous neuroblastoma CDX models by injecting human neuroblastoma cells into the adrenal gland and the flanks of immunodefici...

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Detalles Bibliográficos
Autores principales: Han, Rui, Zhao, Wenjie, Gu, Xu, Gao, Xue, Yang, Yong-Guang, Zhang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908914/
https://www.ncbi.nlm.nih.gov/pubmed/35197367
http://dx.doi.org/10.18632/aging.203913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908914/
https://www.ncbi.nlm.nih.gov/pubmed/35197367
http://dx.doi.org/10.18632/aging.203913

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