Cargando…

Different tumorigenicity and distinct metastasis and gene signature between orthotopic and subcutaneous neuroblastoma xenografted mice

Patient-derived (PDX) and cell-derived (CDX) xenograft models are widely used in preclinical studies of human neuroblastoma. In this study, we constructed orthotopic and subcutaneous neuroblastoma CDX models by injecting human neuroblastoma cells into the adrenal gland and the flanks of immunodefici...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Rui, Zhao, Wenjie, Gu, Xu, Gao, Xue, Yang, Yong-Guang, Zhang, Xiaoling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908914/ https://www.ncbi.nlm.nih.gov/pubmed/35197367 http://dx.doi.org/10.18632/aging.203913

Ejemplares similares

Development and characterization of a human orthotopic neuroblastoma xenograft
por: Stewart, Elizabeth, et al.
Publicado: (2015)

In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma
por: Whitehouse, Jacqueline P., et al.
Publicado: (2023)

Survival following complete resection of neuroblastoma in novel orthotopic rat xenograft model
por: Sever, ReidAnn E., et al.
Publicado: (2023)

The effect of chemotherapeutic agents on tumor vasculature in subcutaneous and orthotopic human tumor xenografts
por: Fung, Andrea S, et al.
Publicado: (2015)

Identification and causes of metabonomic difference between orthotopic and subcutaneous xenograft of pancreatic cancer
por: Zhan, Bohan, et al.
Publicado: (2017)

Difference in morphology and interactome profiles between orthotopic and subcutaneous gastric cancer xenograft models
por: Nakano, Kiyotaka, et al.
Publicado: (2018)

Neuroblastoma patient-derived orthotopic xenografts retain metastatic patterns and geno- and phenotypes of patient tumours
por: Braekeveldt, Noémie, et al.
Publicado: (2015)

Longitudinal characterization of primary osteosarcoma and derived subcutaneous and orthotopic relapsed patient-derived xenograft models
por: da Costa, Maria Eugenia Marques, et al.
Publicado: (2023)

Development and optimization of orthotopic liver metastasis xenograft mouse models in uveal melanoma
por: Sugase, Takahito, et al.
Publicado: (2020)

MicroRNAs define distinct human neuroblastoma cell phenotypes and regulate their differentiation and tumorigenicity
por: Samaraweera, Leleesha, et al.
Publicado: (2014)

3D Multicellular Stem-Like Human Breast Tumor Spheroids Enhance Tumorigenicity of Orthotopic Xenografts in Athymic Nude Rat Model
por: Mokhtari, Reza Bayat, et al.
Publicado: (2021)

Regression of orthotopic neuroblastoma in mice by targeting the endothelial and tumor cell compartments
por: Fuchs, Dieter, et al.
Publicado: (2009)

Differential In Vivo Tumorigenicity of Distinct Subpopulations from a Luminal-Like Breast Cancer Xenograft
por: Skrbo, Nirma, et al.
Publicado: (2014)

CF750-A33scFv-Fc-Based Optical Imaging of Subcutaneous and Orthotopic Xenografts of GPA33-Positive Colorectal Cancer in Mice
por: Wei, Danfeng, et al.
Publicado: (2015)

Neuroblastoma patient-derived xenograft cells cultured in stem-cell promoting medium retain tumorigenic and metastatic capacities but differentiate in serum
por: Persson, Camilla U., et al.
Publicado: (2017)

Triptolide inhibits cell proliferation and tumorigenicity of human neuroblastoma cells
por: YAN, XIAOMIN, et al.
Publicado: (2015)

Establishment of an orthotopic patient-derived xenograft mouse model using uveal melanoma hepatic metastasis
por: Kageyama, Ken, et al.
Publicado: (2017)

Aminomethylphosphonic acid inhibits growth and metastasis of human prostate cancer in an orthotopic xenograft mouse model
por: Parajuli, Keshab Raj, et al.
Publicado: (2016)

Novel Breast Cancer Brain Metastasis Patient-Derived Orthotopic Xenograft Model for Preclinical Studies
por: Oshi, Masanori, et al.
Publicado: (2020)

Noninvasive Bioluminescence Imaging of AKT Kinase Activity in Subcutaneous and Orthotopic NSCLC Xenografts: Correlation of AKT Activity with Tumor Growth Kinetics()
por: Suchowski, Karina, et al.
Publicado: (2017)

Mesenchymal stem cells accelerated growth and metastasis of neuroblastoma and preferentially homed towards both primary and metastatic loci in orthotopic neuroblastoma model
por: Yu, Jiao-Le, et al.
Publicado: (2021)

Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity
por: Shih, Hung-Ju, et al.
Publicado: (2012)

An Orthotopic Patient-Derived Xenograft (PDX) Model Allows the Analysis of Metastasis-Associated Features in Colorectal Cancer
por: De Angelis, Maria Laura, et al.
Publicado: (2022)

Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts
por: Jäger, Wolfgang, et al.
Publicado: (2014)

Orthotopic Patient-Derived Xenografts of Pediatric Solid Tumors
por: Stewart, Elizabeth, et al.
Publicado: (2017)

Patient-Derived Orthotopic Xenograft (PDOX) Models of Melanoma †
por: Hoffman, Robert M.
Publicado: (2017)

Orthotopic tumours, a hot topic for xenograft models?
por: Zheng, Dali
Publicado: (2019)

9-cis-UAB30, a novel rexinoid agonist, decreases tumorigenicity and cancer cell stemness of human neuroblastoma patient-derived xenografts
por: Marayati, Raoud, et al.
Publicado: (2020)

Intraductal Delivery of Adenoviruses Targets Pancreatic Tumors in Transgenic Ela-myc Mice and Orthotopic Xenografts
por: José, Anabel, et al.
Publicado: (2013)

An orthotopic xenograft model of human nonseminomatous germ cell tumour
por: Douglas, M L, et al.
Publicado: (2001)

Dynamic Quantitative T1 Mapping in Orthotopic Brain Tumor Xenografts()
por: Herrmann, Kelsey, et al.
Publicado: (2016)

FOXP1 inhibits cell growth and attenuates tumorigenicity of neuroblastoma
por: Ackermann, Sandra, et al.
Publicado: (2014)

JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma
por: Wong, Matthew, et al.
Publicado: (2019)

Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models
por: Sabol, Rachel A., et al.
Publicado: (2019)

Evaluation of Anti-Tumorigenic Effects of Diosmetin against Human Colon Cancer Xenografts in Athymic Nude Mice
por: Koosha, Sanaz, et al.
Publicado: (2019)

Intravenously Administered Alphavirus Vector VA7 Eradicates Orthotopic Human Glioma Xenografts in Nude Mice
por: Heikkilä, Jari E., et al.
Publicado: (2010)

Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice
por: Cudalbu, Cristina, et al.
Publicado: (2021)

Patient-derived xenografts as preclinical neuroblastoma models
por: Braekeveldt, Noémie, et al.
Publicado: (2017)

Investigating the Vascular Phenotype of Subcutaneously and Orthotopically Propagated PC3 Prostate Cancer Xenografts Using Combined Carbogen Ultrasmall Superparamagnetic Iron Oxide MRI
por: Burrell, Jake S., et al.
Publicado: (2016)

Generation of orthotopic patient-derived xenografts from gastrointestinal stromal tumor
por: Sicklick, Jason K, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ebhoauft7gcir9qo3bqgckmv92