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The telomere-mitochondrial axis of aging in newborns

Aging starts at the beginning of life as evidenced by high variability in telomere length (TL) and mitochondrial DNA content (mtDNAc) at birth. Whether p53 and PGC-1α are connected to these age-related markers in early life is unclear. In this study, we hypothesized that these hallmarks of aging are...

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Detalles Bibliográficos
Autores principales: Van Der Stukken, Charlotte, Nawrot, Tim S., Alfano, Rossella, Wang, Congrong, Langie, Sabine A.S., Plusquin, Michelle, Janssen, Bram G., Martens, Dries S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908926/
https://www.ncbi.nlm.nih.gov/pubmed/35169104
http://dx.doi.org/10.18632/aging.203897