Inhibition of Heme Export and/or Heme Synthesis Potentiates Metformin Anti-Proliferative Effect on Cancer Cell Lines

SIMPLE SUMMARY: Tumor initiation and progression are sustained by the ability of the cancer cell to reshape its metabolism in a way that favors cell proliferation and survival. Recently, it was shown that heme metabolism contributes to metabolic adaptation of tumor cell and that interfering with hem...

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Detalles Bibliográficos
Autores principales: Allocco, Anna Lucia, Bertino, Francesca, Petrillo, Sara, Chiabrando, Deborah, Riganti, Chiara, Bardelli, Alberto, Altruda, Fiorella, Fiorito, Veronica, Tolosano, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908972/
https://www.ncbi.nlm.nih.gov/pubmed/35267538
http://dx.doi.org/10.3390/cancers14051230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908972/
https://www.ncbi.nlm.nih.gov/pubmed/35267538
http://dx.doi.org/10.3390/cancers14051230

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