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Metformin and ICG-001 Act Synergistically to Abrogate Cancer Stem Cells-Mediated Chemoresistance in Colorectal Cancer by Promoting Apoptosis and Autophagy

SIMPLE SUMMARY: Colorectal cancer (CRC) is one of the most frequently diagnosed and lethal malignancies. The majority of CRC patients experience disease relapse after the primary curative treatment strategy of surgery followed by 5FU-based chemotherapy. The presence of cancer stem-like cells (CSCs)...

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Detalles Bibliográficos
Autores principales: Roy, Souvick, Zhao, Yinghui, Yuan, Yate-Ching, Goel, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908991/
https://www.ncbi.nlm.nih.gov/pubmed/35267590
http://dx.doi.org/10.3390/cancers14051281