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Metformin and ICG-001 Act Synergistically to Abrogate Cancer Stem Cells-Mediated Chemoresistance in Colorectal Cancer by Promoting Apoptosis and Autophagy
SIMPLE SUMMARY: Colorectal cancer (CRC) is one of the most frequently diagnosed and lethal malignancies. The majority of CRC patients experience disease relapse after the primary curative treatment strategy of surgery followed by 5FU-based chemotherapy. The presence of cancer stem-like cells (CSCs)...
Autores principales: | Roy, Souvick, Zhao, Yinghui, Yuan, Yate-Ching, Goel, Ajay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908991/ https://www.ncbi.nlm.nih.gov/pubmed/35267590 http://dx.doi.org/10.3390/cancers14051281 |
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