Adipose Triglyceride Lipase Deficiency Attenuates In Vitro Thrombus Formation without Affecting Platelet Activation and Bleeding In Vivo

According to genome-wide RNA sequencing data from human and mouse platelets, adipose triglyceride lipase (ATGL), the main lipase catalyzing triglyceride (TG) hydrolysis in cytosolic lipid droplets (LD) at neutral pH, is expressed in platelets. Currently, it is elusive to whether common lipolytic enz...

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Detalles Bibliográficos
Autores principales: Goeritzer, Madeleine, Schlager, Stefanie, Kuentzel, Katharina B., Vujić, Nemanja, Korbelius, Melanie, Rainer, Silvia, Kolb, Dagmar, Mussbacher, Marion, Salzmann, Manuel, Schrottmaier, Waltraud C., Assinger, Alice, Schlagenhauf, Axel, Madreiter-Sokolowski, Corina T., Blass, Sandra, Eichmann, Thomas O., Graier, Wolfgang F., Kratky, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908992/
https://www.ncbi.nlm.nih.gov/pubmed/35269472
http://dx.doi.org/10.3390/cells11050850