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Adipose Triglyceride Lipase Deficiency Attenuates In Vitro Thrombus Formation without Affecting Platelet Activation and Bleeding In Vivo
According to genome-wide RNA sequencing data from human and mouse platelets, adipose triglyceride lipase (ATGL), the main lipase catalyzing triglyceride (TG) hydrolysis in cytosolic lipid droplets (LD) at neutral pH, is expressed in platelets. Currently, it is elusive to whether common lipolytic enz...
Autores principales: | Goeritzer, Madeleine, Schlager, Stefanie, Kuentzel, Katharina B., Vujić, Nemanja, Korbelius, Melanie, Rainer, Silvia, Kolb, Dagmar, Mussbacher, Marion, Salzmann, Manuel, Schrottmaier, Waltraud C., Assinger, Alice, Schlagenhauf, Axel, Madreiter-Sokolowski, Corina T., Blass, Sandra, Eichmann, Thomas O., Graier, Wolfgang F., Kratky, Dagmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908992/ https://www.ncbi.nlm.nih.gov/pubmed/35269472 http://dx.doi.org/10.3390/cells11050850 |
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