Targeting of RecQ Helicases as a Novel Therapeutic Strategy for Ovarian Cancer

SIMPLE SUMMARY: Ovarian cancer is the most lethal gynecologic malignancy and is characterized by genomic instability and DNA repair defects. PARP inhibitors (PARPi) changed the treatment paradigm of ovarian cancer but the development of resistance to PARPi is a pressing clinical challenge. In this r...

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Detalles Bibliográficos
Autores principales: Maity, Jyotirindra, Horibata, Sachi, Zurcher, Grant, Lee, Jung-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909030/
https://www.ncbi.nlm.nih.gov/pubmed/35267530
http://dx.doi.org/10.3390/cancers14051219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909030/
https://www.ncbi.nlm.nih.gov/pubmed/35267530
http://dx.doi.org/10.3390/cancers14051219

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