Cargando…
Targeting of RecQ Helicases as a Novel Therapeutic Strategy for Ovarian Cancer
SIMPLE SUMMARY: Ovarian cancer is the most lethal gynecologic malignancy and is characterized by genomic instability and DNA repair defects. PARP inhibitors (PARPi) changed the treatment paradigm of ovarian cancer but the development of resistance to PARPi is a pressing clinical challenge. In this r...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909030/ https://www.ncbi.nlm.nih.gov/pubmed/35267530 http://dx.doi.org/10.3390/cancers14051219 |