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Deep Learning-Based Pan-Cancer Classification Model Reveals Tissue-of-Origin Specific Gene Expression Signatures

SIMPLE SUMMARY: Gene expression data from different cancer types offer the opportunity to identify cancer tissue-of-origin specific biomarkers and targets. In this study, we used pan-cancer gene expression data to train a deep learning neural network model to identify cancer tissue-of-origin specifi...

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Detalles Bibliográficos
Autores principales: Divate, Mayur, Tyagi, Aayush, Richard, Derek J., Prasad, Prathosh A., Gowda, Harsha, Nagaraj, Shivashankar H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909043/
https://www.ncbi.nlm.nih.gov/pubmed/35267493
http://dx.doi.org/10.3390/cancers14051185