Cargando…

Monocarboxylate Transporters Are Involved in Extracellular Matrix Remodelling in Pancreatic Ductal Adenocarcinoma

SIMPLE SUMMARY: Monocarboxylate transporters (MCTs) carry a variety of substrates, with MCT1–4 being well-characterised and involved in the proton-coupled transport of monocarboxylates (such as lactate), which can be used as metabolic fuel for cancer cells. Increased acidity of the tumour microenvir...

Descripción completa

Detalles Bibliográficos
Autores principales: Ufuk, Ayşe, Garner, Terence, Stevens, Adam, Latif, Ayşe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909080/
https://www.ncbi.nlm.nih.gov/pubmed/35267606
http://dx.doi.org/10.3390/cancers14051298