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Matrix Metalloproteinase-1 (MMP1) Upregulation through Promoter Hypomethylation Enhances Tamoxifen Resistance in Breast Cancer

SIMPLE SUMMARY: Cancer recurrence caused by tamoxifen resistance hampers chemotherapy in breast cancer patients. The reasons behind the resistance were investigated by screening epigenetically regulated genes through analysis of methylation data from tamoxifen-resistant MCF-7 cells. MMP1 locus was f...

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Detalles Bibliográficos
Autores principales: Kim, Hyeon Woo, Park, Jae Eun, Baek, Minjae, Kim, Heejoo, Ji, Hwee Won, Yun, Sung Hwan, Jeong, Dawoon, Ham, Juyeon, Park, Sungbin, Lu, Xinpei, Kang, Han-Sung, Kim, Sun Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909089/
https://www.ncbi.nlm.nih.gov/pubmed/35267540
http://dx.doi.org/10.3390/cancers14051232