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Matrix Metalloproteinase-1 (MMP1) Upregulation through Promoter Hypomethylation Enhances Tamoxifen Resistance in Breast Cancer
SIMPLE SUMMARY: Cancer recurrence caused by tamoxifen resistance hampers chemotherapy in breast cancer patients. The reasons behind the resistance were investigated by screening epigenetically regulated genes through analysis of methylation data from tamoxifen-resistant MCF-7 cells. MMP1 locus was f...
Autores principales: | Kim, Hyeon Woo, Park, Jae Eun, Baek, Minjae, Kim, Heejoo, Ji, Hwee Won, Yun, Sung Hwan, Jeong, Dawoon, Ham, Juyeon, Park, Sungbin, Lu, Xinpei, Kang, Han-Sung, Kim, Sun Jung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909089/ https://www.ncbi.nlm.nih.gov/pubmed/35267540 http://dx.doi.org/10.3390/cancers14051232 |
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