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Severe COVID-19 Shares a Common Neutrophil Activation Signature with Other Acute Inflammatory States

Severe COVID-19 patients present a clinical and laboratory overlap with other hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH). However, the underlying mechanisms of these conditions remain to be explored. Here, we investigated the transcriptome of 1596 individuals, incl...

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Detalles Bibliográficos
Autores principales: Schimke, Lena F., Marques, Alexandre H. C., Baiocchi, Gabriela Crispim, de Souza Prado, Caroline Aliane, Fonseca, Dennyson Leandro M., Freire, Paula Paccielli, Rodrigues Plaça, Desirée, Salerno Filgueiras, Igor, Coelho Salgado, Ranieri, Jansen-Marques, Gabriel, Rocha Oliveira, Antonio Edson, Peron, Jean Pierre Schatzmann, Cabral-Miranda, Gustavo, Barbuto, José Alexandre Marzagão, Camara, Niels Olsen Saraiva, Calich, Vera Lúcia Garcia, Ochs, Hans D., Condino-Neto, Antonio, Overmyer, Katherine A., Coon, Joshua J., Balnis, Joseph, Jaitovich, Ariel, Schulte-Schrepping, Jonas, Ulas, Thomas, Schultze, Joachim L., Nakaya, Helder I., Jurisica, Igor, Cabral-Marques, Otávio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909161/
https://www.ncbi.nlm.nih.gov/pubmed/35269470
http://dx.doi.org/10.3390/cells11050847