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Superoxide Dismutase-3 Downregulates Laminin α5 Expression in Tumor Endothelial Cells via the Inhibition of Nuclear Factor Kappa B Signaling

SIMPLE SUMMARY: Tumor-infiltrating lymphocytes determine cancer prognosis and the response to immunotherapy. The balance of laminin-α4/laminin-α5 isoforms in the endothelial basement membrane plays an instructive function in regulating the diapedesis of immune cells under inflammatory conditions. Pr...

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Detalles Bibliográficos
Autores principales: Carmona-Rodríguez, Lorena, Martínez-Rey, Diego, Martín-González, Paula, Franch, Mónica, Sorokin, Lydia, Mira, Emilia, Mañes, Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909228/
https://www.ncbi.nlm.nih.gov/pubmed/35267534
http://dx.doi.org/10.3390/cancers14051226