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Understanding Retinoblastoma Post-Translational Regulation for the Design of Targeted Cancer Therapies
SIMPLE SUMMARY: Rb1 is a regulator of cell cycle progression and genomic stability. This review focuses on post-translational modifications, their effect on Rb1 interactors, and their role in intracellular signaling in the context of cancer development. Finally, we highlight potential approaches to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909233/ https://www.ncbi.nlm.nih.gov/pubmed/35267571 http://dx.doi.org/10.3390/cancers14051265 |