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Understanding Retinoblastoma Post-Translational Regulation for the Design of Targeted Cancer Therapies

SIMPLE SUMMARY: Rb1 is a regulator of cell cycle progression and genomic stability. This review focuses on post-translational modifications, their effect on Rb1 interactors, and their role in intracellular signaling in the context of cancer development. Finally, we highlight potential approaches to...

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Detalles Bibliográficos
Autores principales: Janostiak, Radoslav, Torres-Sanchez, Ariadna, Posas, Francesc, de Nadal, Eulàlia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909233/
https://www.ncbi.nlm.nih.gov/pubmed/35267571
http://dx.doi.org/10.3390/cancers14051265