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Lysosomal ATP Transporter SLC17A9 Controls Cell Viability via Regulating Cathepsin D

SLC17A9 (solute carrier family 17 member 9) functions as an ATP transporter in lysosomes as well as other secretory vesicles. SLC17A9 inhibition or silence leads to cell death. However, the molecular mechanisms causing cell death are unclear. In this study, we report that cell death induced by SLC17...

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Detalles Bibliográficos
Autores principales: Huang, Peng, Cao, Qi, Xu, Mengnan, Dong, Xian-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909234/
https://www.ncbi.nlm.nih.gov/pubmed/35269509
http://dx.doi.org/10.3390/cells11050887