Cargando…
Lysosomal ATP Transporter SLC17A9 Controls Cell Viability via Regulating Cathepsin D
SLC17A9 (solute carrier family 17 member 9) functions as an ATP transporter in lysosomes as well as other secretory vesicles. SLC17A9 inhibition or silence leads to cell death. However, the molecular mechanisms causing cell death are unclear. In this study, we report that cell death induced by SLC17...
Autores principales: | Huang, Peng, Cao, Qi, Xu, Mengnan, Dong, Xian-Ping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909234/ https://www.ncbi.nlm.nih.gov/pubmed/35269509 http://dx.doi.org/10.3390/cells11050887 |
Ejemplares similares
-
Lysosomal chloride transporter CLH-6 protects lysosome membrane integrity via cathepsin activation
por: Zhang, Qianqian, et al.
Publicado: (2023) -
A lysosomal K(+) channel regulates large particle phagocytosis by facilitating lysosome Ca(2+) release
por: Sun, Xue, et al.
Publicado: (2020) -
Insights into the Interaction of Lysosomal Amino Acid Transporters SLC38A9 and SLC36A1 Involved in mTORC1 Signaling in C2C12 Cells
por: Wang, Dan, et al.
Publicado: (2021) -
Upregulation of IGF2R evades lysosomal dysfunction-induced apoptosis of cervical cancer cells via transport of cathepsins
por: Takeda, Takashi, et al.
Publicado: (2019) -
Therapeutic potential of lysosomal cathepsins for neurodegenerative diseases
por: Prieto Huarcaya, Susy, et al.
Publicado: (2022)