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Disruption of Claudin-Made Tight Junction Barriers by Clostridium perfringens Enterotoxin: Insights from Structural Biology

Claudins are a family of integral membrane proteins that enable epithelial cell/cell interactions by localizing to and driving the formation of tight junctions. Via claudin self-assembly within the membranes of adjoining cells, their extracellular domains interact, forming barriers to the paracellul...

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Detalles Bibliográficos
Autores principales: Ogbu, Chinemerem P., Roy, Sourav, Vecchio, Alex J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909277/
https://www.ncbi.nlm.nih.gov/pubmed/35269525
http://dx.doi.org/10.3390/cells11050903