miRNA-Dependent Regulation of AKT1 Phosphorylation

The phosphoinositide-3-kinase (PI3K)/AKT pathway regulates cell survival and is over-activated in most human cancers, including ovarian cancer. Following growth factor stimulation, AKT1 is activated by phosphorylation at T308 and S473. Disruption of the AKT1 signaling pathway is sufficient to inhibi...

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Detalles Bibliográficos
Autores principales: Frederick, Mallory I., Siddika, Tarana, Zhang, Pengcheng, Balasuriya, Nileeka, Turk, Matthew A., O’Donoghue, Patrick, Heinemann, Ilka U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909289/
https://www.ncbi.nlm.nih.gov/pubmed/35269443
http://dx.doi.org/10.3390/cells11050821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909289/
https://www.ncbi.nlm.nih.gov/pubmed/35269443
http://dx.doi.org/10.3390/cells11050821

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