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Cancer Cells Promote Phenotypic Alterations in Hepatocytes at the Edge of Cancer Cell Nests to Facilitate Vessel Co-Option Establishment in Colorectal Cancer Liver Metastases

SIMPLE SUMMARY: Tumour cells in colorectal cancer liver metastases (CRCLM) obtain their blood supply via two major mechanisms: (i) sprouting angiogenesis, through the generation of new vessels; (ii) vessel co-option, where the cancer cells hijack the pre-existing vasculature. The current treatment f...

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Detalles Bibliográficos
Autores principales: Rada, Miran, Tsamchoe, Migmar, Kapelanski-Lamoureux, Audrey, Hassan, Nour, Bloom, Jessica, Petrillo, Stephanie, Kim, Diane H., Lazaris, Anthoula, Metrakos, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909291/
https://www.ncbi.nlm.nih.gov/pubmed/35267627
http://dx.doi.org/10.3390/cancers14051318