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Epigenetic Alteration of the Cancer-Related Gene TGFBI in B Cells Infected with Epstein–Barr Virus and Exposed to Aflatoxin B1: Potential Role in Burkitt Lymphoma Development

SIMPLE SUMMARY: Endemic Burkitt lymphoma is an aggressive pediatric cancer whose etiological factors include Epstein–Barr virus (EBV) infection and malaria or environmental carcinogen exposures, such as aflatoxin B1 (AFB1). As evidence suggests B cell methylome remodeling to be a transformation mech...

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Detalles Bibliográficos
Autores principales: Manara, Francesca, Jay, Antonin, Odongo, Grace Akinyi, Mure, Fabrice, Maroui, Mohamed Ali, Diederichs, Audrey, Sirand, Cecilia, Cuenin, Cyrille, Granai, Massimo, Mundo, Lucia, Hernandez-Vargas, Hector, Lazzi, Stefano, Khoueiry, Rita, Gruffat, Henri, Herceg, Zdenko, Accardi, Rosita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909323/
https://www.ncbi.nlm.nih.gov/pubmed/35267594
http://dx.doi.org/10.3390/cancers14051284