Testing for Lynch Syndrome in Endometrial Carcinoma: From Universal to Age-Selective MLH1 Methylation Analysis

SIMPLE SUMMARY: International guidelines recommend universal screening of endometrial carcinoma patients for Lynch syndrome, a hereditary cancer predisposition syndrome. Screening is based on mismatch repair protein immunohistochemistry and reflex MLH1 methylation analysis to exclude the likely spor...

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Detalles Bibliográficos
Autores principales: Pasanen, Annukka, Loukovaara, Mikko, Kaikkonen, Elina, Olkinuora, Alisa, Pylvänäinen, Kirsi, Alhopuro, Pia, Peltomäki, Päivi, Mecklin, Jukka-Pekka, Bützow, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909331/
https://www.ncbi.nlm.nih.gov/pubmed/35267656
http://dx.doi.org/10.3390/cancers14051348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909331/
https://www.ncbi.nlm.nih.gov/pubmed/35267656
http://dx.doi.org/10.3390/cancers14051348

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