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Genomic Instability Is Defined by Specific Tumor Microenvironment in Ovarian Cancer: A Subgroup Analysis of AGO OVAR 12 Trial

SIMPLE SUMMARY: Given the importance of genomic instability signatures in the management of ovarian cancer and the difficulties in defining the role of immunotherapy, our objective was to describe the tumor immune microenvironment in the light of genomic instability signatures. Intratumoral CD3(+) T...

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Detalles Bibliográficos
Autores principales: Fumet, Jean-David, Lardenois, Emilie, Ray-Coquard, Isabelle, Harter, Philipp, Joly, Florence, Canzler, Ulrich, Truntzer, Caroline, Tredan, Olivier, Liebrich, Clemens, Lortholary, Alain, Pissaloux, Daniel, Leary, Alexandra, Pfisterer, Jacobus, Eeckhoutte, Alexandre, Hilpert, Felix, Fabbro, Michel, Caux, Christophe, Alexandre, Jérôme, Houlier, Aurélie, Sehouli, Jalid, Sohier, Emilie, Kimmig, Rainer, Dubois, Bertrand, Spaeth, Dominique, Treilleux, Isabelle, Frenel, Jean-Sébastien, Herwig, Uwe, Le Saux, Olivia, Bendriss-Vermare, Nathalie, du Bois, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909387/
https://www.ncbi.nlm.nih.gov/pubmed/35267497
http://dx.doi.org/10.3390/cancers14051189