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Past, Current, and Future Strategies to Target ERG Fusion-Positive Prostate Cancer

SIMPLE SUMMARY: In addition to its role in development and in the vascular and hematopoietic systems, ERG plays a central role in prostate cancer. Approximately 40–50% of prostate cancer cases are characterized by ERG gene fusions, which lead to ERG overexpression. Importantly, inhibition of ERG act...

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Detalles Bibliográficos
Autores principales: Lorenzin, Francesca, Demichelis, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909394/
https://www.ncbi.nlm.nih.gov/pubmed/35267426
http://dx.doi.org/10.3390/cancers14051118