Targeting HIF-2α in the Tumor Microenvironment: Redefining the Role of HIF-2α for Solid Cancer Therapy

SIMPLE SUMMARY: Hypoxia is defined as the inadequate supply of oxygen in tissues. Regions of acute and chronic hypoxia are a universal feature of the tumor microenvironment and a known driver of tumor progression and therapeutic resistance. As oxygen levels decrease, transcription factor HIF-1α and...

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Detalles Bibliográficos
Autores principales: Davis, Leah, Recktenwald, Matthias, Hutt, Evan, Fuller, Schuyler, Briggs, Madison, Goel, Arnav, Daringer, Nichole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909461/
https://www.ncbi.nlm.nih.gov/pubmed/35267567
http://dx.doi.org/10.3390/cancers14051259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909461/
https://www.ncbi.nlm.nih.gov/pubmed/35267567
http://dx.doi.org/10.3390/cancers14051259

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