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Pyk2 Regulates MAMs and Mitochondrial Dynamics in Hippocampal Neurons

Pyk2 is a non-receptor tyrosine kinase enriched in hippocampal neurons, which can be activated by calcium-dependent mechanisms. In neurons, Pyk2 is mostly localised in the cytosol and dendritic shafts but can translocate to spines and/or to the nucleus. Here, we explore the function of a new localis...

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Detalles Bibliográficos
Autores principales: López-Molina, Laura, Fernández-Irigoyen, Joaquín, Cifuentes-Díaz, Carmen, Alberch, Jordi, Girault, Jean-Antoine, Santamaría, Enrique, Ginés, Silvia, Giralt, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909471/
https://www.ncbi.nlm.nih.gov/pubmed/35269464
http://dx.doi.org/10.3390/cells11050842