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Metabolomic Profiling and Mechanotransduction of Single Chondrocytes Encapsulated in Alginate Microgels

Articular cartilage is comprised of two main components, the extracellular matrix (ECM) and the pericellular matrix (PCM). The PCM helps to protect chondrocytes in the cartilage from mechanical loads, but in patients with osteoarthritis, the PCM is weakened, resulting in increased chondrocyte stress...

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Detalles Bibliográficos
Autores principales: Fredrikson, Jacob P., Brahmachary, Priyanka P., Erdoğan, Ayten E., Archambault, Zachary K., Wilking, James N., June, Ronald K., Chang, Connie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909502/
https://www.ncbi.nlm.nih.gov/pubmed/35269522
http://dx.doi.org/10.3390/cells11050900