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Metabolomic Profiling and Mechanotransduction of Single Chondrocytes Encapsulated in Alginate Microgels
Articular cartilage is comprised of two main components, the extracellular matrix (ECM) and the pericellular matrix (PCM). The PCM helps to protect chondrocytes in the cartilage from mechanical loads, but in patients with osteoarthritis, the PCM is weakened, resulting in increased chondrocyte stress...
Autores principales: | Fredrikson, Jacob P., Brahmachary, Priyanka P., Erdoğan, Ayten E., Archambault, Zachary K., Wilking, James N., June, Ronald K., Chang, Connie B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909502/ https://www.ncbi.nlm.nih.gov/pubmed/35269522 http://dx.doi.org/10.3390/cells11050900 |
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