Chromatin Remodeler Smarca5 Is Required for Cancer-Related Processes of Primary Cell Fitness and Immortalization

Smarca5, an ATPase of the ISWI class of chromatin remodelers, is a key regulator of chromatin structure, cell cycle and DNA repair. Smarca5 is deregulated in leukemia and breast, lung and gastric cancers. However, its role in oncogenesis is not well understood. Chromatin remodelers often play dosage...

Descripción completa

Detalles Bibliográficos
Autores principales: Thakur, Shefali, Cahais, Vincent, Turkova, Tereza, Zikmund, Tomas, Renard, Claire, Stopka, Tomáš, Korenjak, Michael, Zavadil, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909548/
https://www.ncbi.nlm.nih.gov/pubmed/35269430
http://dx.doi.org/10.3390/cells11050808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909548/
https://www.ncbi.nlm.nih.gov/pubmed/35269430
http://dx.doi.org/10.3390/cells11050808

Ejemplares similares