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Paclitaxel Induces Epidermal Molecular Changes and Produces Subclinical Alterations in the Skin of Gynecological Cancer Patients

SIMPLE SUMMARY: Skin toxicity is one of paclitaxel’s adverse effects. However, its real impact on the skin could be underestimated as these alterations can also appear asymptomatic. We have observed that paclitaxel modifies gene and protein expression of skin markers in a 3D epidermis model, and imp...

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Detalles Bibliográficos
Autores principales: Montero, Paula, Pérez-Leal, Martín, Pérez-Fidalgo, Jose Alejandro, Sanz, Celia, Estornut, Cristina, Roger, Inés, Milara, Javier, Cervantes, Andrés, Cortijo, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909563/
https://www.ncbi.nlm.nih.gov/pubmed/35267454
http://dx.doi.org/10.3390/cancers14051146