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Modulation of Intestinal Epithelial Permeability via Protease-Activated Receptor-2-Induced Autophagy

Protease-activated receptor 2 (PAR2) alleviates intestinal inflammation by upregulating autophagy. PAR2 also modulates tight junctions through β-arrestin signaling. Therefore, we investigated the effect of PAR2-induced autophagy on intestinal epithelial tight junctions and permeability. RT-PCR, West...

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Detalles Bibliográficos
Autores principales: Kim, Yuju, Lee, Yunna, Heo, Gwangbeom, Jeong, Sihyun, Park, Soyeong, Yoo, Jin-Wook, Jung, Yunjin, Im, Eunok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909592/
https://www.ncbi.nlm.nih.gov/pubmed/35269499
http://dx.doi.org/10.3390/cells11050878