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The B-Cell-Specific Ablation of B4GALT1 Reduces Cancer Formation and Reverses the Changes in Serum IgG Glycans during the Induction of Mouse Hepatocellular Carcinoma

SIMPLE SUMMARY: As serum IgG glycosylation is associated with various cancers, our goal is to explore whether serum IgG galactosylation and its associated glycans could be used as tumor markers associated with hepatocellular carcinoma (HCC). At the same time, we explore the effect of the B-cell-spec...

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Detalles Bibliográficos
Autores principales: Sha, Jichen, Zhang, Rongrong, Fan, Jiteng, Gu, Yong, Pan, Yiqing, Han, Jing, Xu, Xiaoyan, Ren, Shifang, Gu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909634/
https://www.ncbi.nlm.nih.gov/pubmed/35267641
http://dx.doi.org/10.3390/cancers14051333