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CRISPR/Cas9-Mediated Models of Retinitis Pigmentosa Reveal Differential Proliferative Response of Müller Cells between Xenopus laevis and Xenopus tropicalis

Retinitis pigmentosa is an inherited retinal dystrophy that ultimately leads to blindness due to the progressive degeneration of rod photoreceptors and the subsequent non-cell autonomous death of cones. Rhodopsin is the most frequently mutated gene in this disease. We here developed rhodopsin gene e...

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Detalles Bibliográficos
Autores principales: Parain, Karine, Lourdel, Sophie, Donval, Alicia, Chesneau, Albert, Borday, Caroline, Bronchain, Odile, Locker, Morgane, Perron, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909648/
https://www.ncbi.nlm.nih.gov/pubmed/35269429
http://dx.doi.org/10.3390/cells11050807